Research in Progress

As a medication use quality researcher, PQA is engaged in a variety of projects and initiatives related to Medication Adherence & Safety, Medication Access & Social Determinants of Health, Patient Engagement, and Pharmacy Services. PQA has more than a dozen active research projects.

Focus Areas: (click on focus area to reach section)

  • Medication Adherence & Safety
    PQA investigates the impact of medication use quality by studying the impacts of medication adherence and safety. Many of our projects generate evidence for PQA quality measures.
  • Medication Access & SDOH
    PQA research is committed to improving care by targeting patients’ unmet social needs and evaluating the barriers to accessing medications.
  • Patient Engagement
    PQA research conducts patient-centered studies that focus on patient experience and patient engagement to incorporate the patient voice in quality.
  • Pharmacy Services
    As pharmacy practice continues to evolve, PQA is committed to investigating the value of pharmacist-provided care models bring to healthcare teams and patient outcomes.

Medication Adherence & Safety

Relationships between medication adherence, patient costs, and economic outcomes

Methodology: Secondary Data Analysis

Collaborators: Merck, University of Mississippi

Description: This retrospective cohort study aims to describe the relationships of patient out-of-pocket costs on medication adherence and subsequent economic outcomes, describe the interplay of medication adherence quality measures and economic outcomes, and identify proportion of days covered (PDC) levels where outcomes are optimized.

Validation of the COPD Treatment Ratio in a quality measure context

Methodology: Secondary Data Analysis

Collaborators: GlaxoSmithKline

Description: This retrospective cohort study aims to validate the optimal predictive value of the COPD treatment ratio (CTR) as a measure of COPD exacerbation risk in Medicare advantage and commercial line of business samples and explore the suitability for CTR use in a quality measure context.

Reducing opioid overprescribing for common surgical procedures

Methodology: Program Implementation & Evaluation

Collaborators: Johns Hopkins University

Description: This prospective, Improving Wisely interventional study will evaluate the impact of an individual, provider-level peer-to-peer benchmarked opioid prescribing report intervention on opioid prescribing for common surgical procedures.

Adherence to dual antiplatelet therapy

Methodology: Secondary Data Analysis

Collaborators: Pharmacy Quality Solutions

Description: This retrospective cohort study aims to describe and compare adherence to P2Y12 inhibitors and examine factors related to adherence.

Medication Access & SDOH ⇑ top

SDOH data procurement and use among key healthcare stakeholders

Methodology: Survey

Collaborators: Texas Center for Outcomes Research and Education

Description: A cross-sectional survey fielded to PQA members will describe social determinants of health (SDOH) data collection capabilities and associated barriers and facilitators to the collection and use of these data.

Impact of patient out-of-pocket costs for oral anticancer medications on medication adherence

Methodology: Secondary Data Analysis

Collaborators: National Pharmaceutical Council, University of Rhode Island

Description: This retrospective cohort study will evaluate trends and relationships between oral anticancer medication patient out-of-pocket costs and medication adherence. This project was selected from the PQA-NPC request for proposals to address medication access barriers.

Impact of a real time prescription benefit tool on medication access

Methodology: Program Implementation & Evaluation

Collaborators: National Pharmaceutical Council, Johns Hopkins University

Description: This project will investigate the impact of a real time prescription benefit tool on access to new prescriptions. This project was selected from the PQA-NPC request for proposals to address medication access barriers.

Examination of pharmacy accessibility in two racially diverse metropolitan areas

Methodology: Literature Review, Secondary Data Analysis

Collaborators: University of Arizona

Description: The purpose of this study is to develop a model to classify levels of pharmacy access in two racially diverse urban communities.

Patient Engagement ⇑ top

Capturing patient perspectives of comprehensive medication reviews

Methodology: Qualitative

Collaborators: Merck, University of Arizona

Description: This study aims to conceptualize and develop a patient-reported comprehensive medication review experience questionnaire.

Pharmacy Services ⇑ top

Factors influencing specialty pharmacy turnaround time

Methodology: Qualitative, Survey

Collaborators: National Association of Specialty Pharmacy, Pfizer

Description: A series of focus groups with specialty pharmacists and a cross-sectional survey will be used to determine factors that influence specialty pharmacy turnaround time and identify best practices for improving turnaround times.

Evaluating the impact of pharmacist-provided care on medication use, health, and economic outcomes

Methodology: Program implementation & evaluation

Collaborators: Humana, Walgreens, Pfizer

Description: This prospective, randomized study will evaluate the impact of pharmacist-provided care on medication use, health, and economic outcomes in patients with diabetes.

Pharmacist-conducted immunization assessment and documentation

Methodology: Program implementation & evaluation

Collaborators: DocStation

Description: This proof-of-concept pilot study aims to evaluate the routine immunization status assessment documentation in a medication therapy management (MTM) program to increase adult immunization rates.

Forming consensus on measures that demonstrate the value of community pharmacy practice

Methodology: Convening

Collaborators: Community Pharmacy Foundation, multi-stakeholder panel

Description: A series of multi-stakeholder summit meetings are underway to identify and prioritize measure concepts that align with innovative pharmacy services.