PQA Research Portfolio

Advancing Research in Medication Use Quality

PQA has a portfolio of completed research projects that showcase the wide variety of projects and initiatives resulting from interdisciplinary collaboration with member organizations and quality stakeholders.

Completed Research


Inform Medication Quality Measure Development and Implementation

Validation of an Insulin Adherence/Persistence Methodology

  • Partners: Multi-stakeholder Roundtable
  • Description: Given the known complexity of measuring adherence/persistence to injectable treatments and the lack of a quality measure that assesses adherence/persistence to insulin, PQA convened a multi-stakeholder roundtable to identify potential methodologies that PQA further validated for consideration within a quality performance measure.

Demonstrate the Effectiveness of PQA’s Measures

The Impact of PQA Adherence Measures on Health Outcomes

  • Partners: University of Arizona, Merck & Co.
  • Description: PQA medication adherence measures for hypertension (Renin Angiotensin System (RAS) antagonists), cholesterol (statins), and diabetes medications (excluding insulin) are used to evaluate health plan performance in the Medicare Five-Star Quality Rating System. Limited evidence exists regarding the impact of medication adherence on economic outcomes. Researchers at PQA, the University of Arizona, and Merck & Co. investigated the relationship between PQA’s three adherence metrics on healthcare utilization and expenditures.

Promote Best Practices in Medication Use Quality

Impact of the Appointment-based Model on Health Outcomes

  • Partners: Humana, Publix, and Winn-Dixie
  • Description: The ABM is a pharmacy operations model that utilizes medication synchronization and an appointment with the pharmacist for a medication review. ABMs reduce the number of trips to a pharmacy, improve medication adherence and patient satisfaction. PQA conducted a study to investigate the impact of the ABM of medication synchronization on medical outcomes (e.g., adherence, associated cost) of patients with targeted chronic diseases (e.g., diabetes).

Improving Adult Immunization Rates & EQuIPP

  • Partners: Rite Aid, Humana, Pharmacy Quality Solutions, CECity
  • Description: Adult vaccination coverage rates remain well below Healthy People 2020 targets. Improving vaccination rates requires successful information exchange and care coordination between the multiple critical players: the physician, the pharmacist, and the patient. This study investigated whether a pharmacist-led intervention could improve vaccination rates for pneumonia and influenza among individuals enrolled in Medicare Advantage Prescription Drug plans with Humana, Inc.

Immunization Services Model for Adult Rate Improvement

  • Partners: Scientific Technologies Corporation, Voiceport, Kinney Drugs, Price Chopper, Tops Market
  • Description: This study investigated the impact of telephonic immunization prompts during regular automated outbound communiqués on vaccination rate improvement among adult patients across community pharmacies in the Northeastern US.
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